{"id":11,"date":"2017-11-14T13:13:22","date_gmt":"2017-11-14T12:13:22","guid":{"rendered":"https:\/\/www.alveolelab.com\/?page_id=11"},"modified":"2019-06-24T22:19:33","modified_gmt":"2019-06-24T20:19:33","slug":"technologie-bioingenierie","status":"publish","type":"page","link":"https:\/\/www.alveolelab.com\/fr\/technologie-bioingenierie\/","title":{"rendered":"La technologie de bio-ing\u00e9nierie PRIMO"},"content":{"rendered":"
[vc_row el_class=\u00a0\u00bbnarrower\u00a0\u00bb css=\u00a0\u00bb.vc_custom_1511355354915{padding-top: 0px !important;padding-bottom: 150px !important;}\u00a0\u00bb][vc_column][vc_column_text]\n

Le challenge du microenvironnement cellulaire in vitro<\/em><\/h2>\n

In vivo<\/em>, le microenvironnement cellulaire a un impact crucial sur la r\u00e9gulation du comportement et des fonctions cellulaires, tels que la diff\u00e9renciation cellulaire, la prolif\u00e9ration et la migration. Cependant, sa complexit\u00e9 biochimique et structurelle limite notre compr\u00e9hension des param\u00e8tres cl\u00e9s r\u00e9gulant le comportement cellulaire.<\/p>\n

In vitro<\/em>, l’un des d\u00e9fis auxquels sont confront\u00e9s les biologistes cellulaires consiste donc \u00e0 travailler avec des microenvironnements contr\u00f4l\u00e9s et reproductibles<\/strong> afin d’\u00e9tudier plus efficacement les cellules vivantes et mod\u00e9liser des pathologies.<\/p>\n[\/vc_column_text][vc_empty_space height=\u00a0\u00bb30px\u00a0\u00bb][vc_column_text]\n

Bio-ing\u00e9nierie PRIMO: La flexibilit\u00e9 de d\u00e9finir et optimiser les conditions in vitro<\/em> comme vous le souhaitez<\/h2>\n

La technologie de bio-ing\u00e9nierie de PRIMO s’appuie sur un module de photopatterning sans masque et sans contact<\/strong> (PRIMO<\/a>) et un logiciel d\u00e9di\u00e9 (Leonardo<\/a>). La plate-forme peut \u00eatre utilis\u00e9e pour structurer des substrats de culture cellulaire par photopolym\u00e9risation et pour fonctionnaliser des substrats de culture cellulaire (rigides ou mous, plats ou microstructur\u00e9s) via le micropatterning.<\/p>\n[\/vc_column_text][vc_empty_space height=\u00a0\u00bb50px\u00a0\u00bb]

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Structuration de substrats<\/h3>\r

– Microfabrication
\n– Hydrogel structuration<\/p>\n<\/div>\r <\/div>\r <\/i> En savoir +<\/span>\r <\/div>\r <\/div>\r <\/a>\r \r

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Fonctionnalisation de surface<\/h3>\r

– Biomolecule micropatterning<\/p>\n<\/div>\r <\/div>\r <\/i> En savoir +<\/span>\r <\/div>\r <\/div>\r <\/a>\r \r

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Structuration et fonctionnalisation de substrats<\/h3>\r

– Complex cell microenvironments<\/p>\n<\/div>\r <\/div>\r <\/i> En savoir +<\/span>\r <\/div>\r <\/div>\r <\/a>\r <\/div>

<\/div>[\/vc_column][\/vc_row]\n<\/div>","protected":false},"excerpt":{"rendered":"

Comme tous les \u00eatres vivants, les cellules sont sensibles \u00e0 l’environnement qui les entoure. La technologie de bio-ing\u00e9nierie PRIMO offre aux biologistes cellulaires la flexibilit\u00e9 n\u00e9cessaire pour cr\u00e9er et ajuster des microenvironnements cellulaires in vitro<\/em> et travailler sur des mod\u00e8les cellulaires plus fiables et reproductibles.<\/p>\n","protected":false},"author":1,"featured_media":197,"parent":0,"menu_order":28,"comment_status":"closed","ping_status":"closed","template":"","meta":{"inline_featured_image":false,"footnotes":""},"class_list":["post-11","page","type-page","status-publish","has-post-thumbnail","hentry","themes-microenvironnement-substrats"],"yoast_head":"\nAlveole - La technologie de bio-ing\u00e9nierie du micro-environnement PRIMO<\/title>\n<meta name=\"description\" content=\"La technologie de Bio-ing\u00e9nierie PRIMO permet de contr\u00f4ler le microenvironnement cellulaire et rend plus fiables et reproductibles vos mod\u00e8les cellulaires.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.alveolelab.com\/fr\/technologie-bioingenierie\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Alveole - 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