{"id":1669,"date":"2017-11-14T13:14:40","date_gmt":"2017-11-14T12:14:40","guid":{"rendered":"https:\/\/www.alveolelab.com\/our-latest-news\/"},"modified":"2018-03-26T09:42:18","modified_gmt":"2018-03-26T07:42:18","slug":"actualites","status":"publish","type":"page","link":"https:\/\/www.alveolelab.com\/fr\/actualites\/","title":{"rendered":"Actualit\u00e9s"},"content":{"rendered":"
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100th PRIMO established in a research lab<\/h3>\r\n
Publi\u00e9 le 25 avril 2022<\/div>\r\n

5 years after marketing its first bioengineering product PRIMO, Alv\u00e9ole completed its 100th<\/sup> customer sale! A major milestone in the company’s growth. Check out the press release to learn more.<\/p>\n<\/div>\r\n Lire la suite<\/span> <\/a>

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Alv\u00e9ole 10th Anniversary<\/h3>\r\n
Publi\u00e9 le 9 d\u00e9cembre 2020<\/div>\r\n

Today is Alv\u00e9ole’s <\/span>10th Anniversary !! Time flies! Already 4 years since we launched PRIMO… New applications, improvements on our <\/span>micropatterning<\/span> technology, our community has grown, our team has evolved. Let’s keep up with the good work and the fun<\/a>!\u00a0<\/span><\/p>\n<\/div>\r\n <\/div>

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Alv\u00e9ole and Leica Microsystems conclude a partnership<\/h3>\r\n
Publi\u00e9 le 29 septembre 2020<\/div>\r\n

We are proud to collaborate with Leica Microsystems <\/span>to ensure you obtain the best cell samples for <\/span>cryo-ET<\/span>! PRIMO <\/span>micropatterning <\/span>+ Leica <\/span>cryo-CLEM <\/span>= Advanced workflow for whole cell cryo-ET<\/span><\/p>\n

Learn more on this partnership<\/a>.<\/p>\n<\/div>\r\n <\/div>

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Cryo-CLEM Webinar series by Elizabeth Wright: First one on June 11, 2020<\/h3>\r\n
Publi\u00e9 le 2 juin 2020<\/div>\r\n

Dr Elizabeth Wright’s team launches a series of cryo-CLEM webinars which will start on June 11, 10am PDT with \u00ab\u00a0Correlative (cryo-)microscopy for cell biology\u00a0\u00bb.<\/p>\n

Register now for the live and Q&A session<\/a>.<\/p>\n<\/div>\r\n <\/div>

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Connect with our scientific team for online conversations<\/h3>\r\n
Publi\u00e9 le 6 avril 2020<\/div>\r\n

Like many of you, we are trying to adapt to the situation, to stay in touch and to keep talking about science<\/span><\/a>! Our R&D team invites you to set small group online discussions on topics related to PRIMO photopatterning system micropatterning<\/span><\/span> and cellular microenvironment.<\/p>\n

Find more info to set a call with our team.<\/a><\/p>\n<\/div>\r\n <\/div>

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Coronavirus epidemic<\/h3>\r\n
Publi\u00e9 le 17 mars 2020<\/div>\r\n

Faced with the epidemic of Coronavirus and following the measures announced by the French government, our offices in Paris, Germany and USA are closed. Our team members are working from home to minimize the risk of contamination.<\/p>\n

Our whole team remains available to answer your scientific or after-sales questions via email or mobile.<\/p>\n

Take care of yourselves.<\/p>\n<\/div>\r\n <\/div>

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Alv\u00e9ole distribution network expansion<\/h3>\r\n
Publi\u00e9 le 7 janvier 2020<\/div>\r\n

In 2019, our user community and our expertise have grown ; and now in 2020 it’s our distribution network’s turn ! We are happy to start the year by announcing the opening of a subsidiary in Fairfax (Virginia), USA and the successful expansion of our distribution network.<\/p>\n<\/div>\r\n <\/div>

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Webcast: Micropatterning on EM grids<\/h3>\r\n
Publi\u00e9 le 15 octobre 2019<\/div>\r\n

Ask your questions live to Dr Leeya Engel during our sponsored Nature Research webcast on \u00ab\u00a0Micropatterning on EM grids: A strategy for improving cell cryo-ET workflow\u00a0\u00bb > Controlling cell positioning within EM grids. Attend our webinar<\/a>.<\/p>\n<\/div>\r\n <\/div>

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New application note: High-throughput micropatterning on 96 well plates<\/h3>\r\n
Publi\u00e9 le 18 juillet 2019<\/div>\r\n

We’ve been challenged a lot for PRIMO to be used for high content screening experiments and cell-based assays<\/strong>. A major drawback until recently was the long illumination time that prevented from using PRIMO for high-throughput micropatterning …<\/span><\/p>\n<\/div>\r\n Lire la suite<\/span> <\/a>

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\u00ab\u00a0Tailoring cryo-electron microscopy grids by photo-micropatterning…\u00a0\u00bb<\/h3>\r\n
Publi\u00e9 le 20 juin 2019<\/div>\r\n

Here comes another paper using PRIMO contactless micropatterning on TEM Grids! \u00ab\u00a0Tailoring cryo-electron microscopy grids by photo-micropatterning for in-cell structural studies\u00a0\u00bb, M. Toro-Nahuelpan et al, BioRxiv, 2019. From Julia Mahamid’s team at EMBL.<\/p>\n

Read the paper<\/a>.<\/p>\n<\/div>\r\n <\/div>

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Paper: Work on collective migration, using micropatterning to mimic spatial confinement of follower cells<\/h3>\r\n
Publi\u00e9 le 18 juin 2019<\/div>\r\n

\u00ab\u00a0Substrate area confinement is a key determinant of cell velocity in collective migration\u00a0\u00bb, Mohammed et al, Nature Physics, 2019. –> They used micropatterning to mimic the spatial confinement experienced by follower cells within epithelial tissues.<\/p>\n

Access the research paper<\/a>.<\/p>\n<\/div>\r\n <\/div>

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NEW: Micropatterns automatic positioning on TEM Grids<\/h3>\r\n
Publi\u00e9 le 13 juin 2019<\/div>\r\n

See how Leonardo offers two ways to generate series of homogeneous micropatterns automatically positioned<\/strong>\u00a0within the mesh of the TEM Grid,\u00a0without damaging its surface<\/strong> (contactless technique): Using one same pattern VS different series of micropatterns on one TEM Grid!<\/p>\n

Watch the tutorial video<\/a>.<\/p>\n<\/div>\r\n <\/div>

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New paper published by Xavier Trepat’s team – IBEC (Spain)<\/h3>\r\n
Publi\u00e9 le 4 juin 2019<\/div>\r\n

\u00ab\u00a0Traction forces at the cytokinetic ring regulate cell division and polyploidy in the migrating zebrafish epicardium\u00a0\u00bb, M. Uroz et al., Nature Materials, 2019.<\/p>\n

So proud to see PRIMO used in this research work! Check Figure 5.<\/p>\n

Read the paper<\/a>.<\/p>\n<\/div>\r\n <\/div>

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PRIMO used for micropatterning cells on TEM Grids – check this paper!<\/h3>\r\n
Publi\u00e9 le 3 juin 2019<\/div>\r\n

Extracellular matrix micropatterning technology for whole cell cryogenic electron microscopy studies. L. Engel et al., BioRxiv, 2019<\/p>\n

Read the preprint<\/a>.<\/p>\n<\/div>\r\n <\/div>

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Engineering 3D microenvironments by hydrogel structuration and functionalization with PRIMO<\/h3>\r\n
Publi\u00e9 le 27 f\u00e9vrier 2019<\/div>\r\n

Aur\u00e9lien Pasturel (PhD candidate, CNRS, Alv\u00e9ole) presents us his work: \u00ab\u00a0Tailoring 3D cell culture templates with common hydrogels\u00a0\u00bb, A Pasturel, BioRxiv, 2018<\/p>\n

Watch the scientific video<\/a>.<\/p>\n<\/div>\r\n <\/div>

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Why we develop life science tools for researchers and new in vitro models<\/h3>\r\n
Publi\u00e9 le 20 f\u00e9vrier 2019<\/div>\r\n

What\u2019s the common point between a laboratory mouse and a Petri dish? See the answer in video<\/a>.<\/p>\n<\/div>\r\n <\/div>

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Focus on Alv\u00e9ole in \u00ab\u00a0News Medical Life Sciences\u00a0\u00bb<\/h3>\r\n
Publi\u00e9 le 18 f\u00e9vrier 2019<\/div>\r\n

Read the interview of Marie-Charlotte Manus from Alv\u00e9ole explaining how PRIMO Bioengineering platform gives the researchers the flexibility to create tailor-made in vitro<\/em> microenvironment for better cell experiments: \u00ab\u00a0Customizing the cellular microenvironment to improve physiological relevance\u00a0\u00bb<\/a><\/p>\n<\/div>\r\n <\/div>

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SLAS 2019: New Product Announcement<\/h3>\r\n
Publi\u00e9 le 23 janvier 2019<\/div>\r\n

In the starting blocks for SLAS 2019<\/b>! Meet us BOOTH 548, we will present the evolution of PRIMO which has grown into an Automated bioengineering<\/b> Platform performing both microfabrication<\/b> & micropatterning<\/b>!<\/p>\n<\/div>\r\n <\/div>

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For all the cell biology enthusiasts, this is a must-see!<\/h3>\r\n
Publi\u00e9 le 21 janvier 2019<\/div>\r\n

Giant cells moving on a building and adapting to obstacles. We are a<\/span>mazed by the CytoMorphoLab team’s creativity and how they used PRIMO bioengineering<\/span><\/span> technology to miniaturise a building to the size of cells<\/span><\/span>! <\/span><\/p>\n

Find more details about the whole project on their website & make sure you watch THE VIDEO<\/a>!<\/span><\/p>\n<\/div>\r\n <\/div>

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Joint Application Note with NanoSurface Biomedical<\/h3>\r\n
Publi\u00e9 le 10 janvier 2019<\/div>\r\n

Are you interested in understanding the role of the extracellular matrix in cell morphology? This application note is for you.<\/p>\n

Check how we worked with Nanosurface Biomedical to micropattern their microstructured substrate.<\/p>\n

Access the Application Note<\/a>.<\/p>\n<\/div>\r\n <\/div>

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New User Publication: Micropatterning and T Lympocytes haptotaxis<\/h3>\r\n
Publi\u00e9 le 3 janvier 2019<\/div>\r\n

Using quantitative antibodies micropatterning with PRIMO and RICM imaging, the team\u00a0studied haptotaxis of T lymphocytes.<\/p>\n

See all our users’ scientific papers<\/a>.<\/p>\n<\/div>\r\n <\/div>

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Merry Christmas<\/h3>\r\n
Publi\u00e9 le 19 d\u00e9cembre 2018<\/div>\r\n

We are ready for Christmas ! We love our micrometric Christmas Tree made of cells… Unfortunately it is too small to decorate our offices.<\/p>\n

Click on \u00ab\u00a0read more\u00a0\u00bb to watch the GIF !<\/p>\n<\/div>\r\n Lire la suite<\/span> <\/a>

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Alv\u00e9ole & Nature Webinar – PRIMO Bioengineering system<\/h3>\r\n
Publi\u00e9 le 4 d\u00e9cembre 2018<\/div>\r\n

Did you miss our live webinar presented by\u00a0Dr. Manuel Th\u00e9ry\u00a0<\/strong>and\u00a0Dr. Harikrishnan Parameswaran<\/strong>? They explained how PRIMO allows to work with controlled and reproducible microenvironments\u00a0in vitro<\/em>\u00a0to more efficiently study living cells and model diseases.<\/p>\n

Register and watch the replay on Nature dedicated webpage<\/a>.<\/p>\n<\/div>\r\n <\/div>

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Alv\u00e9ole, Bioengineering – Webinar Nature.com<\/h3>\r\n
Publi\u00e9 le 9 novembre 2018<\/div>\r\n

Bioengineering Custom Cell Microenvironments with Versatile Maskless Photopatterning<\/p>\n

November 28, 5pm CET<\/p>\n

Dr. Manuel Th\u00e9ry,\u00a0<\/b>CEA, &\u00a0Dr. <\/b>Harikrishnan<\/b> Parameswaran,\u00a0<\/b>Northeastern University<\/p>\n<\/div>\r\n Lire la suite<\/span> <\/a>

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New paper using PRIMO micropatterning<\/h3>\r\n
Publi\u00e9 le 7 novembre 2018<\/div>\r\n

\u00ab\u00a0Optical magnetometry of single biocompatible micromagnets for quantitative magnetogenetic and magnetomechanical assays\u00a0\u00bb, Toraille, A\u00efzel et al, Nano Lett., 2018<\/p>\n

The figure shows HeLa cells micropatterned near micromagnets and injected with magnetic nanoparticules.<\/p>\n

Access the paper<\/a>.<\/p>\n

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Alv\u00e9ole dans Biotech Info 3.0<\/h3>\r\n
Publi\u00e9 le 6 novembre 2018<\/div>\r\n

Biotech Info 3.0 – Alv\u00e9ole : des outils de cr\u00e9ation d’environnements cellulaires in vitro biomim\u00e9tiques, pour des mod\u00e8les cellulaires plus fiables!<\/p>\n

Pour les abonn\u00e9s de Biotech Info 3.0, acc\u00e9der \u00e0 l’article<\/a>.<\/p>\n<\/div>\r\n <\/div>

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PRIMO spotted by Science Magazine<\/h3>\r\n
Publi\u00e9 le 18 octobre 2018<\/div>\r\n

A focus on \u00ab\u00a0Microenvironment Mimics\u00a0\u00bb explains how PRIMO allows researchers to better study living cells in vitro,<\/em> by creating sophisticated and complex in vitro<\/em> microenvironments to better understand and control the key parameters regulating cell functions and behavior.<\/p>\n

Read the article<\/a>.<\/p>\n<\/div>\r\n <\/div>

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EduBourse – DeepTech Fran\u00e7aise, un pari r\u00e9ussi pour Alv\u00e9ole<\/h3>\r\n
Publi\u00e9 le 17 octobre 2018<\/div>\r\n

\u00ab\u00a0Alv\u00e9ole l\u00e8ve 1 million d’euros et valide le mod\u00e8le de son Company Builder Quattrocento.\u00a0\u00bb<\/span><\/p>\n

Acc\u00e9dez \u00e0 l’article publi\u00e9 par EduBourse<\/a>.<\/p>\n<\/div>\r\n <\/div>

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CF News – Alv\u00e9ole prend son autonomie<\/h3>\r\n
Publi\u00e9 le 16 octobre 2018<\/div>\r\n
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Alv\u00e9ole l\u00e8ve 1 million d\u2019euros<\/h3>\r\n
Publi\u00e9 le 16 octobre 2018<\/div>\r\n

Apr\u00e8s une premi\u00e8re phase de financement par Quattrocento depuis 2010 qui permet le lancement r\u00e9ussi de son premier produit PRIMO consacr\u00e9 \u00e0 la cr\u00e9ation de mod\u00e8les cellulaires in vitro <\/em>en 2016, Alv\u00e9ole atteint d\u00e9sormais l\u2019ind\u00e9pendance financi\u00e8re.<\/p>\n

Gr\u00e2ce \u00e0 cette nouvelle lev\u00e9e, Alv\u00e9ole pourra poursuivre le d\u00e9veloppement de ses innovations et enrichir ses \u00e9quipes de nouveaux talents.<\/p>\n<\/div>\r\n Lire la suite<\/span> <\/a>

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Nuit Blanche 2018: Art meets Sciences with the \u00ab\u00a0Living Architectures\u00a0\u00bb film projection<\/h3>\r\n
Publi\u00e9 le 5 octobre 2018<\/div>\r\n

Paris, Centre de Recherches Interdisciplinaires (CRI)<\/strong>, 6 octobre 2018\u00a0– <\/strong>Des cellules artificielles produites \u00e0 partir de cuisses de lapin et de cerveaux de b\u0153uf\u00a0? Mais qu\u2019est-ce que cela vient faire sur la fa\u00e7ade d\u2019un immeuble\u00a0?<\/p>\n<\/div>\r\n Lire la suite<\/span> <\/a>

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ECM stiffness regulates force transmission pathways in multicellular ensembles of human airway smooth muscle cells<\/h3>\r\n
Publi\u00e9 le 31 ao\u00fbt 2018<\/div>\r\n

New paper by researchers from Harvard U<\/span>n<\/span>iversity<\/span> and Northeastern University<\/span> using PRIMO contacltess and maskless photopatterning, show\u00a0\u00ab\u00a0ECM stiffness can act as a switch that regulates whether forces are transmitted via the ECM or through cell-cell contacts\u00a0\u00bb.<\/p>\n

Access our users’ papers.<\/a><\/p>\n<\/div>\r\n <\/div>

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New paper: The cytoskeleton as a smart composite material…<\/h3>\r\n
Publi\u00e9 le 20 ao\u00fbt 2018<\/div>\r\n

Abstract: The interrelationship between microtubules and the actin cytoskeleton in mechanoregulation of integrin-mediated adhesions is poorly understood. Here, we show that the effects of microtubules on two major types of cell-matrix adhesions,…\u00a0Read paper.<\/a><\/p>\n

See more papers using PRIMO.<\/a><\/p>\n<\/div>\r\n <\/div>

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New paper: hydrogel structuration in 3D & biochemical functionalization<\/h3>\r\n
Publi\u00e9 le 10 ao\u00fbt 2018<\/div>\r\n

The Institute for Interdisciplinary Neuroscience, Universit\u00e9 de Bordeaux, CNRS, in collaboration with Alv\u00e9ole shows PRIMO can create complex microenvironments for cells from hydrogel structuration to precise functionalization.<\/p>\n

\u00ab\u00a0A generic widefield topographical and chemical photopatterning method for hydrogels.\u00a0\u00bb<\/a><\/p>\n<\/div>\r\n <\/div>

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Maxime Dahan<\/h3>\r\n
Publi\u00e9 le 1 ao\u00fbt 2018<\/div>\r\n

C\u2019est avec beaucoup d\u2019\u00e9motion que nous avons appris le d\u00e9c\u00e8s de Maxime Dahan le 30 Juillet dernier. Son d\u00e9c\u00e8s brutal laisse place \u00e0 l\u2019incompr\u00e9hension, et la brutalit\u00e9 de sa disparition touche tous les membres de l\u2019\u00e9quipe.<\/p>\n<\/div>\r\n Lire la suite<\/span> <\/a>

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PRIMO at University of Geneva<\/h3>\r\n
Publi\u00e9 le 12 juillet 2018<\/div>\r\n

Last week we were at <\/span>The University of Geneva<\/span> to instal PRIMO after a successful demo! <\/span><\/p>\n

Pau Guillamat from Aur\u00e9lien Roux’ lab uses PRIMO contactess and maskless micropatterning to study epithelial dynamics. <\/span><\/p>\n

Check some of his previous work with PRIMO<\/a>.<\/span><\/p>\n<\/div>\r\n <\/div>

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Made in Woods Hole<\/h3>\r\n
Publi\u00e9 le 9 juillet 2018<\/div>\r\n

The team who loaned a PRIMO for this year Physiology Summer Course at the Marine Biological Laboratory made quite an experiment!<\/p>\n

To study cell junctions under curvature, they patterned MDCK cells on a spiral fibronectin pattern.<\/p>\n

Check the video<\/a>.<\/p>\n<\/div>\r\n <\/div>

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PRIMO back to the MBL (Woods Hole, USA)<\/h3>\r\n
Publi\u00e9 le 20 juin 2018<\/div>\r\n

Yay, we are back to the Marine Biological Laboratory!\u2069<\/p>\n

This year with 2 micropatterning PRIMO systems installed:<\/p>\n

1 for the MBL Physiology Summer course<\/p>\n

+ 1 for Dr Edgar Gomes’ (iMM Lisboa) summer lab who is already enjoying it !<\/p>\n<\/div>\r\n <\/div>

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Alv\u00e9ole \u00e0 Bercy pour pr\u00e9senter PRIMO r\u00e9compens\u00e9 par le \u00ab\u00a0Prix Jean Jerphagnon\u00a0\u00bb<\/h3>\r\n
Publi\u00e9 le 5 juin 2018<\/div>\r\n

Romuald Vally, CEO d\u2019Alv\u00e9ole, et Vincent Studer, co-fondateur d’Alv\u00e9ole, \u00e9taient invit\u00e9s au Minist\u00e8re de l\u2019Economie et des Finances pour pr\u00e9senter Alv\u00e9ole et sa technologie de contr\u00f4le du microenvironnement cellulaire PRIMO.<\/p>\n<\/div>\r\n Lire la suite<\/span> <\/a>

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Alv\u00e9ole becomes a distributor of SuSoS Anti-fouling coatings<\/h3>\r\n
Publi\u00e9 le 18 mai 2018<\/div>\r\n

After a successful collaboration in developing new types of anti-fouling polymers for cell culture and precise control over cell adhesion, SuSoS and Alv\u00e9ole have now entered into a distribution contract.<\/p>\n<\/div>\r\n Lire la suite<\/span> <\/a>

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New Application Note<\/h3>\r\n
Publi\u00e9 le 15 mai 2018<\/div>\r\n

\u00ab\u00a0Controlling the topography and biochemistry of cell culture substrates with PRIMO\u00a0\u00bb<\/strong><\/p>\n

One of the challenges confronting cell biologists is to mimic the micro-environment\u00a0in vitro<\/em>\u00a0to more efficiently study living cells. (…) PRIMO allows to tailor cell microenvironment topography via microfabrication and biochemistry via micropatterning…<\/p>\n

Read the application note<\/a><\/p>\n<\/div>\r\n <\/div>

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Cell behavior study by Aurelien Roux’ Lab<\/h3>\r\n
Publi\u00e9 le 30 avril 2018<\/div>\r\n

When you offer cells a choice… Yes they go for the higher protein density! Experiment conducted by Pau Guillamat from Aurelien Roux’ lab – University of Geneva. <\/span><\/p>\n

Watch the video of cells migrating towards two different protein densities in Pau Guillamat’s testimonial<\/a>.<\/span><\/p>\n<\/div>\r\n <\/div>

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Alv\u00e9ole at the British Society for Developmental Biology spring meeting<\/h3>\r\n
Publi\u00e9 le 16 avril 2018<\/div>\r\n

Meet us on Booth 8, ask us all your questions and see how PRIMO custom micropatterning system can help you tune the cell microenvironment chemistry and topography. And thus precisely control cell development and proliferation !<\/p>\n<\/div>\r\n <\/div>

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Rockefeller University – G. M. Alushin PhD<\/h3>\r\n
Publi\u00e9 le 11 avril 2018<\/div>\r\n

Special thanks to the team of the Laboratory of Structural Biophysics & Mechanobiology, <\/span>G<\/span>regory M. Alushin PhD<\/span>,\u00a0<\/span>The Rockefeller University<\/span>, for sending us this picture of them photopatterned with PRIMO custom photopatterning system!\u00a0 <\/span><\/p>\n

We look forward to seeing your experiment results with PRIMO, studying the cytoskeleton!\u00a0<\/span><\/p>\n<\/div>\r\n <\/div>

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New paper by Virgile Viasnoff’s lab using PRIMO and micro-niches<\/h3>\r\n
Publi\u00e9 le 30 mars 2018<\/div>\r\n

Virgile Viasnoff<\/span>‘s lab at the\u00a0<\/span>Mechanobiology Institute –<\/span>\u00a0<\/span>National University of Singapore<\/span> is going further in controlling cell microenvironment in 3D: with micro-niches in which they control chemical, topographical and rheological cues using PRIMO photopatterning system!\u00a0<\/span><\/p>\n

Read their Paper<\/a>.<\/p>\n<\/div>\r\n <\/div>

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PRIMO at Universit\u00e9 de Mons<\/h3>\r\n
Publi\u00e9 le 26 mars 2018<\/div>\r\n

PRIMO<\/a> contactless & maskless photopatterning for controlling topography and chemistry of cellular microenvironment now in DEMO at Universit\u00e9 de Mons\u00a0in the Mechanobiology & Soft Matter Group!<\/p>\n

Want to test it too? Request a demo<\/a>!<\/p>\n<\/div>\r\n <\/div>

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User testimonial – Cell division study<\/h3>\r\n
Publi\u00e9 le 8 mars 2018<\/div>\r\n

See how Jorge Ferreira form i3S, Universidade do Porto used PRIMO custom micropatterning technology to control cellular geometry and impose spatial constraints during mitotic progression.<\/p>\n

And read his feedback<\/a> on PRIMO technology.<\/p>\n<\/div>\r\n <\/div>

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New scientific paper using PRIMO<\/h3>\r\n
Publi\u00e9 le 6 mars 2018<\/div>\r\n

New scientific paper in which PRIMO was used:\u00a0 In situ photo-patterning of pressure-resistant hydrogel membranes with controlled permeabilities in PEGDA microfluidic channels,\u00a0Lab Chip, 2018, Advance Article, J\u00e9r\u00e9my Decock, Mathias Schlenkb and Jean-Baptiste Salmon.<\/span><\/p>\n

Read it here<\/a><\/span><\/p>\n

List of papers using PRIMO here<\/a><\/p>\n<\/div>\r\n <\/div>

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Alv\u00e9ole at Biophysical 2018<\/h3>\r\n
Publi\u00e9 le 14 f\u00e9vrier 2018<\/div>\r\n

Meet us on Booth 319<\/strong> and learn more about PRIMO applications in cell biology by attending our exhibitor presentation<\/strong> with some of our users as special guests<\/strong> on Sunday, February 18 – 12:30pm – Room 6!<\/p>\n

Find the programme of the presentation here<\/a>.<\/p>\n<\/div>\r\n <\/div>

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GeneWorks at Lorne Cancer Conference<\/h3>\r\n
Publi\u00e9 le 8 f\u00e9vrier 2018<\/div>\r\n

Nandor Roczo from GeneWorks – our Australien Distributor – presents PRIMO with a poster at the Lorne Cancer 2018 conference from 8 to 10 February. Don’t miss it!<\/p>\n<\/div>\r\n <\/div>

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Institut Jacques Monod: PRIMO & Leonardo installation\/training<\/h3>\r\n
Publi\u00e9 le 1 f\u00e9vrier 2018<\/div>\r\n

PRIMO and Leonardo installation\/training last week at Cell Adhesion & Mechanics lab<\/span>, Institut Jacques Monod<\/span>: CNRS Research Directors Benoit Ladoux and Ren\u00e9-Marc M\u00e8ge, and PhD candidate Estelle Gauquelin seem to have enjoyed it, and so did we!<\/span><\/p>\n<\/div>\r\n <\/div>

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PRIMO demo in Brno, Czech Republic<\/h3>\r\n
Publi\u00e9 le 31 janvier 2018<\/div>\r\n

Jakub Posp\u00ed\u0161il – PhD student in Dr. Josef Jaros Department of Histology\u00a0& Embryology at Faculty of Medicine, Masarykova univerzita – working on his first pattern with PRIMO custom micropatterning for cell control and the new version of Leonardo Photopatterning software.<\/p>\n<\/div>\r\n <\/div>

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New version of Leonardo now available!<\/h3>\r\n
Publi\u00e9 le 24 janvier 2018<\/div>\r\n

The new version of Leonardo software is now available! Discover it on our dedicated webpage<\/a>!<\/span><\/p>\n

In addition to the replication, rotation, alignment, grayscale images management features, you can now define ROIs, program complex experimental sequences and map your samples!<\/span><\/p>\n<\/div>\r\n <\/div>

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PRIMO loan at Universit\u00e9 de Gen\u00e8ve<\/h3>\r\n
Publi\u00e9 le 18 janvier 2018<\/div>\r\n

Pau Guillamat, Postdoctoral Fellow at <\/span>Universit\u00e9 de <\/span>Gen\u00e8ve<\/span> Biochemistry department in Aur\u00e9lien Roux’ Research Group, is testing PRIMO micropatterning solution and Leonardo software.\u00a0<\/span>We’re looking forward to discovering the results!<\/span><\/p>\n<\/div>\r\n <\/div>

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Memories from ASCB 2017<\/h3>\r\n
Publi\u00e9 le 16 janvier 2018<\/div>\r\n

ASCB EMBO 2017 conference official pictures are online<\/a>.\u00a0<\/span>Here Manuel Th\u00e9ry during our in-booth demo. <\/span><\/p>\n

We are looking forward to attending the ASCB<\/span>\u00a0annual meeting again this year and meeting many more interesting people!<\/span><\/p>\n<\/div>\r\n <\/div>

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Happy New Year<\/h3>\r\n
Publi\u00e9 le 2 janvier 2018<\/div>\r\n

Alv\u00e9ole team wishes you a Happy New Year!<\/p>\n

Take some time to reflect on 2017 and then start thinking about new projects for 2018! Looking back on some of our users’ applications PRIMO helped to carry out…<\/p>\n<\/div>\r\n Lire la suite<\/span> <\/a>

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Les Echos: Bordeaux parie sur les neurosciences<\/h3>\r\n
Publi\u00e9 le 12 d\u00e9cembre 2017<\/div>\r\n

Les Echos journal presents the technologies and companies emerging from Bordeaux University Neurosciences Institute, among which you find Alv\u00e9ole and its custom micropatterning technology.<\/p>\n

Read full article (Fr only) on their website.<\/p>\n<\/div>\r\n Lire la suite<\/span> <\/a>

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The Scientist – Image of the day<\/h3>\r\n
Publi\u00e9 le 24 novembre 2017<\/div>\r\n

The Scientist shares one of our experiment which shows how PRIMO micropatterning system allows to study cell migration with a custom micropattern that controls cell microenvironment!
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Combination of micropatterning and super-resolution<\/h3>\r\n
Publi\u00e9 le 31 octobre 2017<\/div>\r\n

2D-STORM image by Abbelight of patterned epithelial cells labelled for Actin on square micropatterns done with PRIMO.<\/p>\n<\/div>\r\n <\/div>

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PRIMO at i3S, Universidade de Porto<\/h3>\r\n
Publi\u00e9 le 20 octobre 2017<\/div>\r\n

Jorge Ferreira (Group leader) and Vanessa Nunes (PHD Student) are testing PRIMO and starting to use it on their own. Here is there first test: photopolymerization of photocurable material shaped in the i3S logo.<\/p>\n<\/div>\r\n <\/div>

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The Paris Grands Prix de l\u2019Innovation (Innovation Trophies): 2017 Finalist<\/h3>\r\n
Publi\u00e9 le 18 octobre 2017<\/div>\r\n

Alv\u00e9ole was selected as a finalist in the Health section of the City of Paris Innovation Trophies. The goal of this contest is to support and reward innovative Parisian companies in quickly growing fields, which develop the economy in Greater Paris. The 2017 Awards Ceremony will be held on December 12 in Paris.<\/p>\n<\/div>\r\n Lire la suite<\/span> <\/a>

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Here\u2019s a Flashy New Technique to Model Disease<\/h3>\r\n
Publi\u00e9 le 9 octobre 2017<\/div>\r\n

Labiotech explains the importance of controlling the microenvironment in order to better study living cells in vitro. They highlight the micropatterning and how PRIMO can make a difference for cell biology researchers.
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Acto-Myosin contraction on a micropattern<\/h3>\r\n
Publi\u00e9 le 6 octobre 2017<\/div>\r\n

The CytomorphoLab team imaged a beautiful video of acto-myosin contraction on a micropattern shaped as our logo and done with PRIMO. Courtesy of Manuel Th\u00e9ry, Laurent Blanchoin, Christophe Gu\u00e9rin, Dmitry Ayollo et Benoit Vianay.
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D\u00e9couvrez comment PRIMO aide les travaux de m\u00e9canobiologie de <\/br>Virgile Viasnoff<\/h3>\r\n
Publi\u00e9 le 28 septembre 2017<\/div>\r\n

The use of PRIMO in this context proved absolutely essential since it allowed us to create\u00a0arti\ufb01cial microniches in 3D\u00a0where we could control up to 150 combinations of environ-mental cues.<\/p>\n<\/div>\r\n Lire la suite<\/span> <\/a>

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PRIMO en pr\u00eat \u00e0 Forschungszentrum J\u00fclich<\/h3>\r\n
Publi\u00e9 le 26 septembre 2017<\/div>\r\n

L\u2019\u00e9quipe du Pr. Rudolf Merkel de Institute of Complex Systems Biomechanics (ICS-7) \u00e0 Forschungszentrum J\u00fclich visualise le r\u00e9sultat du premier micropattern r\u00e9alis\u00e9 par leurs soins avec PRIMO !<\/p>\n<\/div>\r\n <\/div>

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New video tutorials on our \u00ab support \u00bb webpage<\/h3>\r\n
Publi\u00e9 le 18 septembre 2017<\/div>\r\n

Get more details on all the key steps of photopatterning with PRIMO: from drawing your micropatterns to seeding cells on it, plus all technical aspects such as switching on and calibrating the system, or preparing your substrates with an antifouling coating!<\/p>\n<\/div>\r\n Lire la suite<\/span> <\/a>

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PRIMO at the Institute for Bioengineering of Catalonia<\/h3>\r\n
Publi\u00e9 le 12 septembre 2017<\/div>\r\n

Now in Xavier Trepat\u2019s lab! Here is Raimon Sunyer Borrell starting using Leonardo software which controls PRIMO photopatterning system! We are looking forward to seeing your micropatterning experiments conducted with PRIMO.<\/p>\n<\/div>\r\n <\/div>

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Micropatterning and focal adhesions<\/h3>\r\n
Publi\u00e9 le 11 septembre 2017<\/div>\r\n

Epithelial cells plated on a grid micropatterned with PRIMO: Actin (green), focal adhesions (red) and nuclear enveloppe (blue).<\/p>\n<\/div>\r\n <\/div>

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Multiwell PDMS stencils by Alv\u00e9ole<\/h3>\r\n
Publi\u00e9 le 5 septembre 2017<\/div>\r\n

We are glad to announce that we are officially launching the multi-well PDMS Stencils. We have developed this new product in order to facilitate the PRIMO photopatterning experimental manipulations of our users.
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PRIMO at the University of Twente<\/h3>\r\n
Publi\u00e9 le 28 ao\u00fbt 2017<\/div>\r\n

Verena Schwach from Robert Passier\u2019s lab at the University of Twente is preparing her experiments of micropatterning of cardiomyocytes on glass. We are looking forward to discovering her results.<\/p>\n<\/div>\r\n <\/div>

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Micrometric eclipse<\/h3>\r\n
Publi\u00e9 le 21 ao\u00fbt 2017<\/div>\r\n

We witnessed a micrometric solar eclipse over France before the real one happened in the USA! Scale bar = 50\u00b5m<\/p>\n<\/div>\r\n <\/div>

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No limits to your patterns<\/h3>\r\n
Publi\u00e9 le 16 ao\u00fbt 2017<\/div>\r\n

Pattern of the day done with PRIMO, Eiffel Tower in Fibronectin and then with MDCK cells.<\/p>\n<\/div>\r\n <\/div>

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PRIMO now at the Northeastern University<\/h3>\r\n
Publi\u00e9 le 2 ao\u00fbt 2017<\/div>\r\n

Niccole Schaible and Sam Polio from the Northeastern University – Department of Bioengineering – now have a PRIMO! They are using it to study cardiomyocytes on PDMS with direct photopatterning and cell-cell interaction on polyacrylamide gel doing micropatterning transfer.<\/p>\n<\/div>\r\n <\/div>

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Alv\u00e9ole has moved<\/h3>\r\n
Publi\u00e9 le 27 juillet 2017<\/div>\r\n

Here is our new address: 30 rue Campo-Formio, 75013 Paris, France. More space for continuing our expansion and bigger labs for even better experiments! Discover it for yourself with this time-lapse video.<\/p>\n<\/div>\r\n Lire la suite<\/span> <\/a>

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PRIMO is at Stanford<\/h3>\r\n
Publi\u00e9 le 13 juillet 2017<\/div>\r\n

Proud to have installed a PRIMO at Stanford University! Gaspard Pardon can now start experimenting with it to micropattern proteins on hydrogels in 3D, multi-protein patterning and many other projects!<\/p>\n<\/div>\r\n <\/div>

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Patterning is art<\/h3>\r\n
Publi\u00e9 le 12 juillet 2017<\/div>\r\n

Thibaut Brunet shared on Twitter a picture of cells plated on micropatterns he generated with PRIMO, during the Physiology summer course at the Marine Biological Laboratory (MBL). Imaged by Nikon USA.<\/p>\n<\/div>\r\n <\/div>

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GeneWorks distributes PRIMO<\/h3>\r\n
Publi\u00e9 le 1 avril 2017<\/div>\r\n

Read the full article by The Magazine of the Australian Society for Biochemistry and Molecular Biology<\/p>\n<\/div>\r\n Lire la suite<\/span> <\/a>

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PRIMO ou le photopatterning de motifs en prot\u00e9ines<\/h3>\r\n
Publi\u00e9 le 24 d\u00e9cembre 2016<\/div>\r\n

Read the full article by Spectra Analyse.<\/p>\n<\/div>\r\n Lire la suite<\/span> <\/a>

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Alveole Appoints GeneWorks As Its Exclusive Distributor in Australia<\/h3>\r\n
Publi\u00e9 le 20 d\u00e9cembre 2016<\/div>\r\n

Read the full article by Biospace.<\/p>\n<\/div>\r\n Lire la suite<\/span> <\/a>

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Alveole presents its new PRIMO photopatterning technology at American Society for Cell Biology 2016<\/h3>\r\n
Publi\u00e9 le 11 novembre 2016<\/div>\r\n

Read the full article by Biospace.<\/p>\n<\/div>\r\n Lire la suite<\/span> <\/a>

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Controllo del microambiente cellulare<\/h3>\r\n
Publi\u00e9 le 2 novembre 2016<\/div>\r\n

Read the full article by Laboratorio 2000.<\/p>\n<\/div>\r\n Lire la suite<\/span> <\/a>

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Customized Control of the Cell Microenvironment<\/h3>\r\n
Publi\u00e9 le 1 ao\u00fbt 2016<\/div>\r\n

Read the full article by Genetic Engineering & Biotechnology News<\/p>\n<\/div>\r\n Lire la suite<\/span> <\/a>

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Alv\u00e9ole : pour un contr\u00f4le sur mesure du microenvironnement cellulaire<\/h3>\r\n
Publi\u00e9 le 21 juillet 2016<\/div>\r\n

Read the full article by CNRS Innovation<\/p>\n<\/div>\r\n Lire la suite<\/span> <\/a>

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Quattrocento l\u00e8ve 5,2 millions d\u2019euros pour d\u00e9velopper des medtechs<\/h3>\r\n
Publi\u00e9 le 16 juillet 2016<\/div>\r\n

Read the full article by L\u2019Usine Nouvelle.<\/p>\n<\/div>\r\n Lire la suite<\/span> <\/a>

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PRIMO, a new device for creating photopatterns for cellular assays<\/h3>\r\n
Publi\u00e9 le 28 juin 2016<\/div>\r\n

Read the full article by IINS.<\/p>\n<\/div>\r\n Lire la suite<\/span> <\/a>

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PRIMO: offering customized control of the cell microenvironment<\/h3>\r\n
Publi\u00e9 le 27 juin 2016<\/div>\r\n

Read the full article by Teknoscienze Publisher<\/p>\n<\/div>\r\n Lire la suite<\/span> <\/a>

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PRIMO: Offering Customized Control Of The Cell Microenvironment<\/h3>\r\n
Publi\u00e9 le 27 juin 2016<\/div>\r\n

Read the full article by Biospace<\/p>\n<\/div>\r\n Lire la suite<\/span> <\/a>

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PRIMO: Offering Customized Control Of The Cell Microenvironment<\/h3>\r\n
Publi\u00e9 le 27 juin 2016<\/div>\r\n

Read the full article by Teknoscienze Publisher.<\/p>\n<\/div>\r\n Lire la suite<\/span> <\/a>

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PRIMO : le contr\u00f4le sur mesure du microenvironnement cellulaire<\/h3>\r\n
Publi\u00e9 le 27 juin 2016<\/div>\r\n

Read the full article by Cadureso.<\/p>\n<\/div>\r\n Lire la suite<\/span> <\/a>

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Alv\u00e9ole, une ruche d\u2019innovation<\/h3>\r\n
Publi\u00e9 le 27 mai 2016<\/div>\r\n

Read the full article by Biotech Info.<\/p>\n<\/div>\r\n Lire la suite<\/span> <\/a>

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New Product Awards<\/h3>\r\n
Publi\u00e9 le 2 avril 2016<\/div>\r\n

Read the full article by DDNEWS \u2013 Pharma, Biotech & Life science.<\/p>\n<\/div>\r\n Lire la suite<\/span> <\/a>

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