Meet our team online at Cell Bio virtual 2020
DECEMBER 7 – 11, 2020
With a virtual format, this year’s ASCB EMBO annual conference will be quite different from what we are used to. But, eager to adapt, to discover new great research works and to meet you in a new way, our team will once again be present !
This time, meet us on our virtual booth, in one-to-one online meetings or in the virtual networking space ! We will be happy to answer your questions, discuss your experimental projects and present you new applications for cell biology and cryo-ET enabled by the PRIMO micropatterning system.
Attending Cell Bio 2020 and interested in PRIMO ? Schedule a one-to-one discussion, by filling the form at the bottom of this page.
Tech Talk by Alvéole
Digging deeper into cellular mechanisms with micropatterning and cryo-ET
WEDNESDAY 9 DECEMBER, 2:00-2:45pm US EST time (08:00pm-08:45pm CET)
- Dr Pierre-Olivier Strale (Alvéole)
- Dr Leeya Engel (Stanford University)
- Dr Matthijn Vos (Institut Pasteur)
- PhD Student, Léa Swistak (Institut Pasteur)
In this talk we will first present how the PRIMO maskless micropatterning system allows users to generate custom and specific in vitro cell microenvironments – at the subcellular scale – tailored to each specific cell type and study. The custom printing of biomolecules on any cell culture substrate (stiff or soft, flat or microstructured) provides control over cell shape, polarity and location, and the ability to mimic in vivo phenotypes. Thus, PRIMO presents a powerful tool for different fields of biology research, such as mechanobiology, disease modeling, immunology and more recently for cryo-electron tomography (cryo-ET).
In the second part of the talk, Dr Leeya Engel (PostDoc in Alex Dunn’s lab, Stanford University), Dr Matthijn Vos (Head NanoImaging Core Facility, Institut Pasteur) and Léa Swistak (PhD student in Jost Enninga’s lab, Institut Pasteur) will present recent advances in the field of whole-cell cryo-ET and how it facilitates unrivalled molecular insights on intra-cellular organization of cells. They will also emphasize how integrating micropatterning into cellular sample preparation for cryo-ET (i.e., plunge freezing, correlative light microscopy, cryo-FIB lamella milling) improves their throughput and efficiency, thanks to precise cell positioning and optimized cell spreading.
Join this talk to:
- see how micropatterning and cryo-ET can accelerate research breakthroughs on what really goes on in the cellular machinery at the molecular scale!
- and ask the speakers all the questions you have in mind!