Alvéole’s goal is to make the control of living cells the future of cell biology. Since the knowledge that the microenvironment has a crucial impact on the regulation of cell behaviour and functions, biologists have required new tools to more efficiently study cells and model diseases. This is why Alvéole developed PRIMO, a 2D and 3D custom protein micropatterning device that allows to mimic in vitro the physiological conditions and control the development and proliferation of living cells in culture.
PRIMO contactless and maskless micropatterning technology is a so-called subtractive technology. It relies on the combination of structured UV-light and a specific photo-initiator (PLPP) to degrade an anti-fouling coating and allow for precisely localized protein adsorption on cell culture substrates. Therefore a good anti-fouling coating is the starting point for high-quality micropatterning.
Alvéole and SuSoS established a first collaboration in 2015 with the idea of developing these types of anti-fouling, patternable coatings. This collaboration has resulted in a newly signed distribution agreement, which allows Alvéole customers to now order anti-fouling coating polymers, as PLL-g-PEG, and pre-coated coverslips together with Alvéole’s products and consumables. This way, Alvéole enhances its capacity to deliver high-quality service to its customers and offers them the best of micropatterning technology.