Key steps of micropatterning on microstructures with PRIMO
For an easier control over your experiments, Leonardo software automatically detects microstructures to precisely align and project your images onto it.
Substrate structuration and functionalization
Whether on 3D substrates you manufactured yourself or on commercially available ones, PRIMO allows you to micropattern your biomolecules. Create more complex in vitro cell microenvironments and better 3D cell culture systems!
Combining structuration and functionalization for more relevant in vitro cell microenvironments
First, start by generating your substrate with the microstructures and/or the stiffness you want, using PRIMO for microfabrication and/or hydrogel structuration.
Then, functionalize the surface of that substrate with your biomolecule by micropatterning it on the areas you specifically define.
Finally, you have it: a complex and more relevant in vitro cell microenvironment!
Top and bottom of PDMS micro-pillars (100 μm high, spaced by 100 μm) patterned with two different biomolecules.
Do you have a question about your project of experiment with PRIMO?
Our research and application development team can help you set up or optimize your experimental protocols!