Leonardo <br />software
Leonardo
software image/svg+xml
LEONARDO 5
LEONARDO 5
New version and new concept
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Primo <br />optical <br />module
Primo
optical
module image/svg+xml
PRIMO
PRIMO
Bioengineering unleashed
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PDMS <br />stencil
PDMS
stencil image/svg+xml
PDMS Stencil
PDMS Stencil
The multi-well solution
Learn more
PRIMO <br />reagents
PRIMO
reagents image/svg+xml
PRIMO REAGENTS
PRIMO REAGENTS
The photoactivatable product line
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Automated Bioengineering Platform

Better cell sample preparation for better cell models.

Functionalize and/or structure your substrates and generate better in vitro cell models for:

  • enhancing the physiological relevance of your cell biology experiments,
  • screening different conditions,
  • facilitating whole-cell cryo-ET imaging.

Several products, one platform, one objective:

Accelerate your research work,
thanks to an optimized and personalized control over your experimental conditions.

 

PRIMO

Bioengineering unleashed

PRIMO 2, new generation with compact footprint, new optical design allowing epi-fluorescence microscopy and faster performances. Micropatterning, hydrogel polymerization and microfabrication, all in a single device. Create bespoke in vitro cellular microenvironments and get better cell models for your cell biology experiments or cryo-ET studies.
Discover Primo
 

PDMS Stencil

The multi-well solution

With its multiple wells, the PDMS Stencil reduces the volumes of reagents used and accommodates different experimental conditions on the same substrate.
Discover the PDMS Stencil
 

PRIMO REAGENTS

The photoactivatable product line

PRIMO is a UV-based photopatterning system with a diverse range of applications including micropatterning and hydrogel structuration. Our product line supports both of these applications with photoactivable reagents. PLPP Classic: enables high-throughput micropatterning of cell culture substrates when illuminated with PRIMO. PLPP Gel: accelerates the speed of your micropatterning experiments and substrate biofunctionalization up to 30 times compared to PLPP Classic. HyPE: enables to flexibly structure hydrogels in 2.5D, while coupled with UV.
Additional information on the PRIMO reagents
 

LEONARDO 5

New version and new concept

The LEONARDO software has been developed to control the PRIMO system and optimize the usage of its different capabilities. The new LEONARDO 5 is built in modules to improve its ease of use and to save time while performing experiments with PRIMO: micropatterning, EM grids micropatterning, multiwell plates micropatterning, hydrogel structuration, microfabrication, multi-images projection. The new features and modules have been approved and validated by our users.
Discover the features of LEONARDO
 

MICROPATTERNING PLATFORM

New hardware solution with integrated optics

No inverted microscope available for PRIMO2? We are now offering a micropatterning platform with integrated optics. This platform gives you access to the PRIMO2 technology without the need for a dedicated microscope. An all-in-one platform for micropatterning, hydrogel polymerization, and microfabrication. Non-contractual image
Additional information on the micropatterning platform

Controlling
the cellular
microenvironment

Alvéole has developed innovative solutions adapted to all standard cell culture substrates, rigid or soft, in 2D or 3D.

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Applications

See some examples of applications such as the control of cell adhesion, migration and cellular development in 2D and 3D.

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Testimonials

Our users describe their research projects and explain why they chose to use PRIMO!

Read the testimonials

Resources and Support

Our team gives you all the tips to successfully conduct your experimental manipulations and go even further!

Video
tutorials

Scientific
papers

Application notes

See all resources