New hardware solution with integrated optics

No inverted microscope available for PRIMO2?

We are now offering a micropatterning platform with integrated optics.
This platform gives you access to the PRIMO2 technology without the need for a dedicated microscope.

An all-in-one platform for micropatterning, hydrogel polymerization, and microfabrication.

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More information to come.

In the meantime, use the form below to ask for more details, depending on your experiments and application.

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If you would like to test PRIMO on one of your experimental projects, receive a quote or simply to know more about Alvéole and its products

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For an optimized and personalized control over your experimental conditions, discover complementary PRIMO products.



Bioengineering unleashed

PRIMO 2, new generation with compact footprint, new optical design allowing epi-fluorescence microscopy and faster performances. Micropatterning, hydrogel polymerization and microfabrication, all in a single device. Create bespoke in vitro cellular microenvironments and get better cell models for your cell biology experiments or cryo-ET studies.
Discover Primo

PDMS Stencil

The multi-well solution

With its multiple wells, the PDMS Stencil reduces the volumes of reagents used and accommodates different experimental conditions on the same substrate.
Discover the PDMS Stencil


The photoactivatable product line

PRIMO is a UV-based photopatterning system with a diverse range of applications including micropatterning and hydrogel structuration. Our product line supports both of these applications with photoactivable reagents. PLPP Classic: enables high-throughput micropatterning of cell culture substrates when illuminated with PRIMO. PLPP Gel: accelerates the speed of your micropatterning experiments and substrate biofunctionalization up to 30 times compared to PLPP Classic. HyPE: enables to flexibly structure hydrogels in 2.5D, while coupled with UV.
Additional information on the PRIMO reagents


New version and new concept

The LEONARDO software has been developed to control the PRIMO system and optimize the usage of its different capabilities. The new LEONARDO 5 is built in modules to improve its ease of use and to save time while performing experiments with PRIMO: micropatterning, EM grids micropatterning, multiwell plates micropatterning, hydrogel structuration, microfabrication, multi-images projection. The new features and modules have been approved and validated by our users.
Discover the features of LEONARDO

Resources and Support

Our team gives you all the tips to successfully conduct your experimental manipulations and go even further!



Application notes

See all resources