Tune pattern geometries
PRIMO allows a precise control of the cell adhesion to elucidate its impact on the intracellular cytoskeleton organization of a single cell. This makes it a perfect tool to study isolated cells under reproducible conditions.
Change cell confinement to elucidate intrinsic cellular forces
Here, they wanted to demonstrate how localized modulation of cell rheology governs cell-cell contact. The geometric constraints impose different cortical stiffness in single, doublets or triplets of cells.