Engineering 3D microenvironments by hydrogel structuration and functionalization with PRIMO

Date: February 26, 2019


Video speakers:

  • Aurélien Pasturel PhD candidate, CNRS, IINS, Alvéole
  • Dr. Pierre-Olivier Strale, Alvéole

In this scientific video, we meet with one of our users who presents us a synthesis of his recent research work using PRIMO bioengineering platform. PRIMO Bioengineering technology is first presented by Dr. Pierre-Olivier Strale (Senior scientist at Alvéole). Then Aurélien Pasturel (PhD candidate, CNRS, Alvéole) presents us his work on hydrogel structuration and biofunctionalization for more relevant cell microenvironments and better cell culture. This work is preprint in BioRxiv: ” Tailoring 3D cell culture templates with common hydrogels. ” A. Pasturel et al., BioRxiv, 2018, doi:

Bioengineering custom cell microenvironments with PRIMO contactless photopatterning

Date: November 28, 2018


Webinar speakers:

  • Dr. Manuel Théry, Research Director, CEA in Hospital Saint Louis, Paris
  • Dr. Harikrishnan Parameswaran, Assistant Professor, Northeastern University

One of the challenges confronting cell biologists is to work with controlled and reproducible microenvironments in vitro to more efficiently study living cells and model diseases. This webinar presents a versatile and contactless photopatterning system, PRIMO, that allows researchers to engineer custom in vitro microenvironments and fine-tune their mechanical (microfabrication with photoresist, microstructuration of hydrogels) and biochemical properties (protein micropatterning), at the micrometer scale with high flexibility and reproducibility.

The speakers will show how this technology opens new possibilities for a large range of applications from sub-cellular to multi-cellular level: cytoskeleton organization, focal adhesions, cell migration, stem cell differentiation, single cell confinement in microwells, tissue engineering, drug testing, disease modelling – with a focus on asthma and the use of extracellular matrix micropatterning to study force transmission in a two-cell ensemble of human airway smooth muscle cells.

PRIMO: the first quantitative multi-protein photopatterning solution

Date: April 13, 2016


Webinar speakers:

  • Dr. Luc Talini – Alvéole
  • Dr. Vincent Studer – IINS, University of Bordeaux
  • Dr. Pierre-Olivier Strale – IINS, University of Bordeaux

Watch the recording of the webinar organized by Alvéole to present PRIMO, this innovative photopatterning technology, the range of applications it covers in cell biology, and answer researchers’ questions live.